The products offered on this website (except supplements) are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
All articles and product information provided on this website is for informational and educational purposes only.
00071 S
New product
Nootropic Research, Antidepressant Research, Vigilance Research, Neuroprotection Research, Therapeutic effects in Alzheimer's disease, ASD (Autism) Research, Anti-Aging Research, Neurodegenerative disease. Purchase a 30 ml of bacteriostatic water separately. One 30ml bottle will be enough for multiple vials of peptides.
Taltirelin - 100mg
Nootropic Research, Antidepressant Research, Vigilance Research, Neuroprotection Research, Therapeutic effects in Alzheimer's disease, ASD (Autism) Research, Anti-Aging Research, Neurodegenerative disease. Purchase a 30 ml of bacteriostatic water separately. One 30ml bottle will be enough for multiple vials of peptides.
Recipient :
* Required fields
or Cancel
Taltirelin has been marketed primarily for its effiacy as an Anti-Spinocerebellar Degeneration Agent. Taltirelin is a biased superagonist at TRH-R1 with a unique profile of efficacy.
One of the first cited studies back in 2002 shows this chemical, taltirelin, to be neuroprotective. This effect was exerted even with models of ischemia and other conditions that are hard to treat.
However, studies on it's neuroprotective, and moreover, pro-cognitive / nootropic effects date back to 1997; where it was demonstrated to have ameliorated consiousness impairment, memory impairment and motor dysfunction in several models. In 2007, a much larger study showed taltirelin to be a potent antinociceptive (pain relieving) ) as well, an effect at least partly, but certainly not solely, dependent on the indirect activation of serotonin 5-HT A receptors.
The larger wonders of this chemical began in 2013,with tests showing marvelous anti-depressant effects and even more significant, the demonstrations of it being almost unprecedented, and even comparable to methamphetamine (but not dangerous and without adverse events) in inducing/increasing dopamine release.
It was also demonstrated to have acute and chronic memory enhancement effects and could ameliorate memory impairment on a central hypothalamic level and by directly modulating cholinergic neurotransmission in the hippocampus, a brain area largely involved with spatial, active and declarative memory.
An anti-ataxic effect of taltirelin was noted as well - an effect that probably has to do with NMDA-glutamate receptor modulation/activation, as this benefit was blocked by an NMDA-antagonist; MK-801.
Taltirelin was also revealed to have nootropic. Brain cells and synapses increasing and this occurred at the molecular and central level. The most profound effects were seen in the spinal cord, though it was also noted to reverse nerve damage in other tissues/brain regions.
Taltirelin's effects on Neurotransmission:
• Taltirelin increases extracellular levels of acetylcholine in the hippocampus, but modulates turnover if levels are already high (potentially protecting against excesses of ACh as well).
• Taltirelin increases noradrenaline in the hypothalamus.
• Taltirelin super-potently increases dopamine release in the striatum and nucleus accumbens, which are area's involved in motivation and as such this is likely the responsible action for it's pungent anti-depressant effects.
• The compound also can regulate/increase serotonin levels in the brain stem. nucleus accumbens and striatum.
• Taltirelin may increase neurite outgrowth via distinct modulation of neurotrophic factors and via positive effects on blood flow.
In summary, Taltirelin has demonstrated the following effects/benefits:
• As an anti-depressant.
• As a nootropic.
• Ameliorating memory deficits, and increasing retention.
• As a novel analgesic/pain reliever.
• As a stimulant, with motivation increasing effects.
• Regenerating spinal cord nerves and treating spinal muscular atrophy.
• Rapidly increasing dopamine, noradrenaline, serotonin and acetylcholine.
• Amelioration of Autism Spectrum Diorder (ASD) and Obsessive-Compulsive Disorder (OCD) conditions.
• Fosters a superior state of arousal and vigilance.
• Increases cerebral metabolism and blood flow.
Some suggested clinical indications for TRH analogs:
• Depression, especially accompanied by hypersomnolence
• Chronic fatigue syndromes
• Excessive daytime sleepiness (including narcolepsy), neurasthenia,
• and lethargy
• Sedation secondary to drugs, chemotherapy, or radiation therapy
• Sedative intoxication/respiratory distress (ER setting)
• Recovery from general anesthesia
• Attention deficit/hyperactive disorder
• Disturbances of circadian rhythm (e.g. jet lag)
• Bipolar affective disorder as a mood stabilizer
• Anxiety disorders
• Alzheimer’s disease and other dementias with cognition deficits
• Seizure disorders
• Motor neuron disorders
• May be particularly effective as adjunctive therapy
Ingredients:Taltirelin
Formula: C17H23N7O5
Chain: (1-methyl-4,5-dihydroorotyl)- His-Pro-NH2
CAS: 103300-74-9
Peptide purity: Greater than 98.0%
Shipping Conditions: Ambient temperature only.
Storage: Lyophilised peptide must be stored at -20°C and peptide solution at 4°C. Before mixing, keep between -18 and -20°C. Use within 24 months. Once reconstituted use within 20 days. Do not freeze once reconstituted.
Use: Not for human consumtpion. For research only.
All our peptides have a purity of at least 98%, most higher than 99%. Peptides are susceptible to heat so our peptides are kept as lyophilised powder in temperature-controlled medical fridges until the time of packaging. Shipments are hand-delivered to the post office at specific times in order to avoid exposure to heat for long periods of time while in the care of postal services. This ensures that the peptide you receive is as pure as possible.
ATTENTION: This compound should be used for research purposes only. All chemical compounds have risks. Please consult your physician and understand the available research before consumption. This product is not intended to diagnose, treat, cure, or prevent any disease.
Delivery Terms & Condition
Customer service - Contact us