TISSUE REPAIR ADVANCED FORMULA - 30ml

BPC-157 Arginate Salt , Thymosin Beta 4 Fragment and KPV have undergone extensive research for their ability to promote wound healing and increase rates of tissue repair. These forms can significantly improve the health of the nervous system by reducing inflammation and oxidative stress, protect cells that support neurons and improve the migration of cells that partake in tissue repair. Much research is also being done with these three peptides in the setting of traumatic brain injury, stroke, and neurodegenerative diseases like ALS and Alzheimer's.

BPC-157 ARGINATE SALT

BPC-157 arginate salt is very stable in human gastric juice and boosts the oral bioavailability from less than 3% to greater than 90%. BPC 157 arginate salt is also more stable in varied temperature environments and can resist the effects of UV light. Studies show that just 5% of BPC 157 arginate is degraded after 5 hours in gastric acid as compared to 98% of the acetate salt with oral administration. The enhanced oral bioavailability of the arginate salt makes it the preferred choice in BPC 157 oral research.

Muscle, Tendon, Ligament and Bone Repair

By inducing angiogenic growth factor healing, BPC-157 has a broad range of healing properties. By increasing the activity of endothelial cell activity that line blood vessels, BPC-157 can aid in the repair of muscles, tendons, ligaments and bone.

Cell Growth and Angiogenesis

Research has shown that BPC-157 increases blood vessel growth in all areas of the body. A study of chicken embryos demonstrated that BPC-157 increases vascular growth through the activation of cell surface receptors in the Nitrous Oxide pathway, growing new vessels toward the injury. This implies potential treatment of heart disease, overall cellular repair for life extension, and other general healing.

Anti-Inflammatory and Antioxidant

A study demonstrated that BPC-157 is a powerful antioxidant by reducing free radical formation via the Nitric Oxide system, attenuating duodenal lesions in rats by significantly decreasing oxidative stress.

Wound Healing

In a study with chemical burns, BPC-157 was shown to rapidly accelerate skin healing, inducing granulation tissue formation, reepithelialization, dermal remodeling, and collagen deposition.

THYMOSIN B4 FRAGMENT

Thymosin beta 4 containing 43 amino-acid residues belongs to a family of highly homologous peptides present at high concentrations in various species, cells, and tissues. . Like many naturally occurring proteins, Thymosin Beta 4 is a very long peptide sequence therefore has to be administered Sub-Q only. It is not orally or intranasally bioavailable. Researchers found that a region that contains just 7 amino acids (LKKTETQ), retains most of the larger protein’s effects when it comes to cell migration, actin polymerization, and wound healing. This fragmented section is referred to as Thymosin beta 4 Fragment.

Because Thymosin beta 4 Fragment is substantially smaller than its parent molecule, its more readily absorbed by the gastrointestinal tract and then by cells. This enhanced oral bioavailability makes Thymosin beta 4 Fragment simpler to administer than the 43 amino acid Thymosin Beta 4.

After injury, Thymosin beta 4, is released by platelets, macrophages and many other cell types to protect cells and tissues from further damage and reduce apoptosis, inflammation and microbial growth. Thymosin beta 4 binds to actin and promotes cell migration, including the mobilization, migration, and differentiation of stem/progenitor cells, which form new blood vessels and regenerate the tissue. Thymosin beta 4 also decreases the number of myofibroblasts in wounds, resulting in decreased scar formation and fibrosis. Thymosin beta 4 also has anti-inflammatory properties and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a number of other conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Thymosin beta 4 quite extensive.

Significantly helps in the healing and repair of muscle, tendon, ligament, joint and bone injuries

Strong anti-inflammatory properties, decreases the amount of inflammatory substances, called cytokines

Increases angiogenesis (new blood vessel formation) around damaged tissue

Improves collagen deposition, tissue healing and cell survival

Increases exchange of substances between cells

Upregulates actin (a vital cellular protein critical to muscle contraction, cell mobility, and signaling between cells)

Supports increase in resistance and strength of muscles, calms muscle spasm and improves muscle tone

Prevents the formation of adhesions and fibrous bands in muscles, tendons, and ligaments

Stretches connective tissue and helps maintain its flexibility

Has cardio and neuroprotective effects

KPV

KPV is a peptide that is naturally produced in the body. It is found in the hormone alpha-MSH. It is used for inflammation, gut health and conditions such as Inflammatory Bowel Disease

Anti-Inflammatory

KPV exerts its anti-inflammatory function inside cells, where it inactivates inflammatory pathways. KPV enters the cell and interacts directly with inflammatory signalling molecules inside the cell. It enters the nucleus of the cell and, once there, can inhibit the interaction of inflammatory substances and molecules.

Anti-Microbial

In addition to its anti‐inflammatory effect, KPV also has antimicrobial effects against pathogens. Its antimicrobial effects were demonstrated on two major pathogens called staphylococcus aureus and Candida albicans. In one study, KPV significantly inhibited staphylococcus aureus from forming colonies.

Wound Healing

Research in wound healing shows KPV can speed wound healing, reduce infection, fight inflammation, and lead to better cosmetic results. Often with wounds, various microbes enter the wound. KPV, with its anti-inflammatory and anti-microbial properties, can be very helpful for combatting these microbes and healing wounds.

It also helps with:

- Cystic acne

- Acne in general

- Eczema

- Psoriasis

- Mold

- Lyme

- Potential help with multiple sclerosis

- inflammatory skin and eye conditions

- allergic asthma

- arthritis..

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DISCLAIMER: This chemical is intendend for lab research and development use only. This product should only be handled by licensed, qualified professionals. This product is not intended to diagnose, treat, cure or prevent any disease.

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REFERENCES:

https://pubmed.ncbi.nlm.nih.gov/20190676/

https://journals.physiology.org/doi/full/10.1152/japplphysiol.00945.2010

https://www.sciencedirect.com/science/article/abs/pii/S875632829800180X

https://pubmed.ncbi.nlm.nih.gov/20388964/

https://www.sciencedirect.com/science/article/abs/pii/S0928425797894740

https://pubmed.ncbi.nlm.nih.gov/9403790/

https://pubmed.ncbi.nlm.nih.gov/22074294/

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056004