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P-21 - 50mg

00040 S

New product

P-21 improve learning and memory, promote neurogenesis and synaptic plasticity.

Purchase a 30 ml of bacteriostatic water separately. One 30ml bottle will be enough for multiple vials of peptides.

79,90 €

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  • P21 is developed from cerebrolysin, which is a peptide. It has a peptide purity of above 98,9 percent. Cerebrolysin is a peptide that has been used to help patients that have suffered from a stroke to recover some of their brain functions. In recent studies it has come to light that this drug can mitigate against an age-dependent decline in learning and memory. This has also been bundled with its neuroprotective qualities. Research is still being carried out on the drug to shed light on other properties that it may have. For its known properties as of now, it’s a very attractive or rather a good candidate for the creation of precognitive medications to treat brain disorders, improve learning and memory, as well as to look to counter diseases such as the Alzheimer’s disease.

    When it was administered in aged rats, it prevented the deficit in neurogenesis and increased expression of the neurotrophic factor of the brain. P21 can increase synaptophysin and synapsin I immunoreactivities. This means that this drug can restore synaptic deficits both in the cortex and hippocampus (hippocampus is the most vulnerable brain region for neurodegeneration). This shows that it can enhance synaptic plasticity. Synaptophysin is a glycoprotein involved in vesicle trafficking machinery by regulating synaptic vesicle exocytosis. The glycoprotein is found in the presynaptic vesicle. When a vivo magnetic resonance spectroscopy is carried out it indicates that there were some dependent alterations in the hippocampal content of several metabolites.

    Another observation that was seen in rats during the experiments was that the level of myoinositol concentration, which was increased in aged rats rather than in young rats, was reduced by P21. This led to conclusions that activating endogenous neuroprotective mechanisms can actually be a viable way of reducing or limiting cognitive ageing, Alzheimer’s, and other disorders that are neurodegenerative in nature.

    P21 has been found to be effective in minimising cell death rates, basically apoptosis, enabling the drug to have insights into the treatment of ischemic stroke, post-operative trauma, and brain contusions.

  • Label Information

    Ingredients:P-21 (with adamantyl group)

    Chain: Ac-DGGL-AG-Nh2 

    CAS: N/A

    Peptide purity: Greater than 98.0%    

    Shipping Conditions: Ambient temperature only.

    Storage: Lyophilised peptide must be stored at -20°C and peptide solution at 4°C. Before mixing, keep between -18 and -20°C. Use within 24 months. Once reconstituted use within 20 days. Do not freeze once reconstituted.

    Use: Not for human consumtpion. For research only.

    Dosage: The dosage is generally 1 milligram a day. There are some instances where acute effects may be wanted. For these cases, some will recommend that two to four milligrams be taken a day/daily. P21 also has an excellent ability to break the blood brain barrier because of its nature. The time to achieve an effect has been shown to be quite long. After administration, it can take up to six months for the effects of p-21 to be observed.

    Side effects: This drug has not been reported to have any side effects. This may be partly due to the fact that very little information is available concerning the drug. In mice that were used to carry out experiments all their behaviours remained the same, meaning no side effects. The only small observation that was noted in some instances was anxiety in the mice that were used in the experiments. So, as research goes on, perhaps we might be able to uncover some details about P21. However, it is clear that P21 does not affect the user's overall body weight, physical state, explanatory behaviour, has no adverse impact on the locomotor skill, and does not result in any signs of depression. These conclusions are based on findings from the experiments carried out on the mice where even their swim speed did not change after administration of P21. Discussions on the side effects of P21 are still ongoing as further studies and research continue.

    Reconstituting: Gently inject 5 ml of bacteriostatic water into the vial. Let it sit in refrigerator for 10 - 15 minutes. If there are any undissolved particles left after 15 minutes, gently rotate the vial between your fingers until all of the powder has dissolved and you are left with clear liquid. 

    All our peptides have a purity of at least 98%, most higher than 99%. Peptides are susceptible to heat so our peptides are kept as lyophilised powder in temperature-controlled medical fridges until the time of packaging. Shipments are hand-delivered to the post office at specific times in order to avoid exposure to heat for long periods of time while in the care of postal services. This ensures that the peptide you receive is as pure as possible.

    ATTENTION: This compound should be used for research purposes only. All chemical compounds have risks. Please consult your physician and understand the available research before consumption. This product is not intended to diagnose, treat, cure, or prevent any disease.

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